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Bird Flu Fears By Carole Nickerson, GlobalBirdFlu.com, Thu Dec 8th
Remember the good old days when a cold consisted of a runnynose, stuffed up sinuses, and a few aches & pains? Or how about the flu? I remember as a kid, the worst horrorstory I ever heard of was someone having a week of diarrhea &vomiting. That was scary stuff, and not even so much in the factthat you would feel downright rotten, but the embarassment of itall. Times have changed....
It seems every year you hear about some crazy new viral mutationor "superbug" sweeping into the population, ready and willing tonot just make us sick, but to outright kill us. Infectious diseases have always been a threat to mankind. In thepast 10 years we have seen many new & reemerging diseases cometo the surface - SARS, Monkeypox, Malaria, Tuberculosis, WestNile Virus, and the most popular of our time - HIV/AIDS. Areport from the National Institute of Allergy and InfectiousDiseases published a 10-year perspective where it showed thatnearly 25% of all worldwide deaths are caused by infectious ¶sitic diseases. That's about 15 million out of some 57million annual deaths. In comes "Bird Flu"...... Technically known as "avian influenza" H5N1, it is the latestinfectious threat on the scene, making headlines around theworld - and for good reason. There have been reports that itcould kill anywhere between 50% - 90% of those infected. It'simportant to remember that opinions & theories are going to varybecause there just isn't enough data to work with inestablishing a true perspective on what h5N1 could do. We doknow that out of 117 reported human cases, 60 were fatal. Thatis indeed a scary number. There is a lot of controversy over the numbers though. Somescientists claim the threat of bird flu is much lower, whileothers predict a global outbreak in the very near future thatcould kill millions. It appears to be yet another issue wherethe "experts" can only guess. People become infected when they come into contact with infectedpoultry and poultry feces, usually during the process ofslaughtering and preparing meat. The World Health Organizationreports though that this does not occur in everyone exposedthough. For many years it has essentially been a diseaseaffecting birds, but over time managed to cross over into athreat to humans. So why the worry? What worries scientists is that if given the right conditions,the H5N1 virus could mutate
Cempra Announces The Completion Of Phase 1 Studies For CEM-101, A Next-Generation Macrolide Cempra Pharmaceuticals announced the successful completion of Phase 1 clinical trials of its oral formulation of CEM-101, which showed good tolerability in those studies. The company also announced plans to submit an IND to the FDA to begin a Phase 1 study with the company's intravenous formulation of CEM-101 in mid-2010... Vaccinating Children For Flu May Help Prevent Transmission, Protect Those Who Are Not Vaccinated Immunizing children and adolescents with inactivated influenza vaccine resulted in reduced rates of influenza in their community compared to a similar community in which children did not receive the vaccine, suggesting that vaccinating children may help prevent transmission of the virus and offer protection for unimmunized community residents, according to a study in the March 10 issue of JAMA... Dr. Alexander Varshavsky And Dr. Harmit Malik Awarded Vilcek Prizes In Biomedical Science The Vilcek Foundation is pleased to announce the granting of the 2010 Vilcek Prize for Biomedical Science to Dr. Alexander Varshavsky, the Howard & Gwen Laurie Smits Professor of Cell Biology at California Institute of Technology, for elucidating the process and biological significance of regulated protein degradation in living cells... Accelr8 Announces Acceptance Of Scientific Presentation, And Pilot Results With A New Rapid Test For A Major Emerging Resistance Threat Accelr8 Technology Corporation (NYSE Amex: AXK) announced that it has received acceptance to present results for a study on 2-hour, culture-free, quantitative pathogen identification. The study was co-authored with principal investigators at the Denver Health Medical Center and the Barnes-Jewish Hospital in St. Louis... What Is Rabies? What Causes Rabies? Rabies is a deadly virus. It is usually transmitted through saliva from the bite of an infected animal, into the bloodstream. The rabies virus is an infection of the central nervous system and causes inflammation of the brain. It is zoonotic, meaning it is transmitted by animals. If treated immediately after a bite, it is possible to prevent rabies... WHO Releases New Malaria Guidelines For Treatment And Procurement Of Medicines The World Health Organization (WHO) is releasing new guidelines for the treatment of malaria, and the first ever guidance on procuring safe and efficacious anti-malarial medicines. In recent years a new type of treatment called artemisinin-based combination therapy (ACTs) has transformed the treatment of malaria, but if not used properly the medicine could become ineffective... Federal Funds Support Health Depts., But Leadership Is Key - Study The surge of funds for bioterrorism preparedness over the past decade does not appear to be improving local public health resources in general, according to research from Purdue University... Chimerix Initiates Phase 2 Study Of CMX001 In Stem Cell Transplant Recipients Seropositive For Cytomegalovirus Chimerix, Inc., a biotechnology company developing orally-available antiviral therapeutics, announced the initiation of a multi-center Phase 2 clinical trial designed to evaluate CMX001 in stem cell transplant recipients who are seropositive for cytomegalovirus (CMV). CMX001 is a broad-spectrum antiviral agent with demonstrated activity against double-stranded DNA (dsDNA) viruses... Tetanus, Hepatitis Vaccination Campaign Launched In Chile Amid Fears Of Disease Outbreaks "Chile launched a hepatitis and tetanus vaccination campaign Friday and doctors warned of outbreaks of diarrhea and infection among thousands of people displaced by the earthquake and the tsunami that heavily damaged or destroyed 36 hospitals and made garbage dumps of coastal towns and cities," the Associated Press reports... Infectious Virus Hidden In Chromosomes During Latency Can Be Passed From Parents To Children Human herpesvirus 6 (HHV-6) infects nearly 100 percent of humans in early childhood, and the infection then lasts for the rest of a person's life... New Research Shows Immune Cells Use Bungee Of Death To Kill Dangerous Cells Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to research published in the Proceedings of the National Academy of Sciences. The study, by researchers from Imperial College London, shows that natural killer (NK) cells use this bungee to destroy cells that could otherwise escape them... Exploring Echinacea's Enigmatic Origins An Agricultural Research Service (ARS) scientist is helping to sort through the jumbled genetics of Echinacea, the coneflower known for its blossoms - and its potential for treating infections, inflammation, and other human ailments... Heat Therapy Shown Effective In Treating Cutaneous Leishmaniasis Among U.S. Soldiers In Iraq A single session of heat therapy using the Thermomed™ device appears to be as effective as a 10-day intravenous course of sodium stibogluconate (Pentostam) for the treatment of Leishmania major skin lesions, according to a new study by Naomi Aronson and her colleagues at the Uniformed Services University of the Health Sciences (USU) and Walter Reed Army Medical Center (WRAMC)... Dissolution Of The Meat Hygiene Service And Merger With The Food Standards Agency The Board of the Food Standards Agency (FSA) has decided to dissolve the executive agency status of the Meat Hygiene Service (MHS) and to bring its staff and functions into the FSA to form the core of a new FSA Operations Group... Xhale Innovations To Demonstrate The HyGreen Hand Hygiene System At The Fifth Decennial International Conference On Healthcare-Associated Infections Xhale Innovations (XI) announced today that it will showcase its hand hygiene system, HyGreen™, at the Fifth Decennial International Conference on Healthcare-Associated Infections to be held March 18 - 22, 2010. This real-time hand hygiene recording and reminding system is designed to assist healthcare facilities with their infection control programs. According to XI CTO, Dr... MicroPhage Seeks FDA Clearance To Market World's First Test Designed To Rapidly Identify Bacterial Infections And Antibiotic Susceptibility MicroPhage announced that it has submitted human data from a pivotal clinical study of its 'Microphage MRSA/MSSA Blood Culture Test' to support a U.S. Food and Drug Administration (FDA) 510(k) premarket notification process. The first of MicroPhage's instrument-free, rapid tests is based on the Company's patented Bacteriophage Amplification platform technology... Max Planck Scientists Develop A Fingerprint For Genes: New Strategy To Play Major Role In Research On Human Diseases Cells may not have a mouth, but they still need to ingest substances from the external environment. If this process - known as endocytosis - is affected, it can lead to infectious diseases or cardio-vascular diseases, cancer, Huntington's and diabetes... Vitamin D Crucial To Activating Immune Defenses Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defenses and that without sufficient intake of the vitamin, the killer cells of the immune system - T cells - will not be able to react to and fight off serious infections in the body... Consumer Advisory - Salmonella In Hydrolysed Vegetable Protein (HVP), Canada The Canadian Food Inspection Agency (CFIA), Health Canada and the Public Health Agency of Canada (PHAC) are closely following an investigation by U.S. authorities into possible Salmonella contamination of Hydrolysed Vegetable Protein (HVP) in the United States. HVP is used as a flavour enhancer in many commercially processed foods... Over-Utilization Of Intravenous Proton Pump Inhibitor In Non-Intensive Care Unit Patients Proton pump inhibitors (PPIs) are the most effective agents for treating acid related gastrointestinal (GI) disorders. The utilization of intravenous (IV) formulations of PPIs has dramatically increased in health care institutions for inappropriate indications, route of administration and length of treatment... Salmonella In HVP Additive Prompts Potentially Massive Processed Food Recall Thousands of types of processed foods containing hydrolyzed vegetable protein or HVP made by Basic Food Flavors Inc in Las Vegas, Nevada, may pose a health risk due to possible contamination with Salmonella Tennessee, said the US Food and Drug Administration last week... Successful Treatment Of Periodontal Disease Lowered Preterm Birth Incidences Previous studies have explored the effect of periodontal treatment, irrespective of efficacy of treatment, in reducing infant prematurity. In a study titled "Risk of Preterm Birth Is Reduced with Successful Periodontal Treatment," lead researcher M. Jeffcott, and colleagues S. Parry and M. Sammel (all from the University of Pennsylvania, Philadelphia) and G. Macones (Washington University, St... Polio Vaccination Campaign To Target 85M Children In 19 West, Central African Countries Global health organizations will launch a $30 million polio vaccination campaign on Saturday in West and Central Africa aimed at immunizing 85 million children under age 5, the Joint Global Polio Eradication Initiative and the International Federation of the Red Cross said on Thursday, Agence France-Presse reports (3/4)... Conference Calls For East African Countries To Prioritize Water, Sanitation Programs During a sanitation conference being held in Kampala, Uganda, this week, "experts have urged regional countries to prioritize programs aimed at increasing access to safe water and sanitation" to move them closer to reaching the Millennium Development Goals (MDGs) target in 2015, New Times/allAfrica.com reports... BioVex Initiates Phase 1 Clinical Trial With Its Genital Herpes Vaccine, ImmunoVEXHSV2 BioVex Inc, a private biotechnology company developing new generation biologics for the treatment of cancer and prevention of infectious disease, announced that the first subject had been dosed in the Phase 1 study of its live attenuated genital herpes vaccine, ImmunoVEXHSV2. The Phase 1 study is an open label ascending dose trial, assessing safety and immune response in healthy volunteers...
into a new form which would allowhuman-to-human infection, sparking a global pandemic. There hasbeen at least one reported case of human-to-human infection inThailand already, so the question now is not "if", but "when" itwill occur. H5N1 is now firmly established in large parts ofAsia, with each human infection giving the virus moreopportunity to adapt and mutate. Based on it's history, makeupand what we've learned from it's cousins & past pandemics, it'sability & likelihood of mutating is very high, making the riskfor a global pandemic a very real possibility. Don't they have anything to treat this? Unfortunately, there is no commercially available product whichcan prevent H5N1 infection in humans. It is under development inseveral countries, but no vaccines are expected to be availablefor several months until after the onset of a pandemic. Theproblem is that they can only guess as to what the virus willlook & behave like in a mutated form. It's like trying to figureout what a 2 month old child will look like when they are 20 andbuying the clothes long before you even know if they'll fit. Most recently, a drug called Tamiflu was being stockpiled bysome countries to combat H5N1, but there are reports that it maynot be very effective at all. Tamiflu was really designed foryour "average joe" flu that we all have has at some point. Inhigher doses, it may work to some degree. Then again, it mightnot. We just don't know that yet. As with everything - there iscontroversy, mixed messages & conflicting expert opinions. Therehave been a number of other vaccines (old & new) being discussedin the news recently. To keep up on the vaccine situation, itprobably best to keep your eye on the WHO website at:http://www.wpro.who.int/health_topics/avian_influenza/ If there is one thing everyone can agree on is that the world isnot prepared. WHO has urged all countries to establishpreparedness plans, but only around 40 have done so and mostdeveloping countries simply don't have the resources to preparethemselves and even fewer have access to vaccines. How ironic that "chicken soup" has been the choice for curingcolds and flus for so many generations. About the author:Carole Nickerson is a writer & web developer who has beenwriting on various topics of interest since 1998. To read moreon the avian bird flu topic, visit GlobalBirdFlu.comKeywords: Bird flu, avian bird flu, asian bird flu, pandemic,bird flu pandemic, birdflu |
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Cempra Announces The Completion Of Phase 1 Studies For CEM-101, A Next-Generation Macrolide Cempra Pharmaceuticals announced the successful completion of Phase 1 clinical trials of its oral formulation of CEM-101, which showed good tolerability in those studies. The company also announced plans to submit an IND to the FDA to begin a Phase 1 study with the company's intravenous formulation of CEM-101 in mid-2010... Vaccinating Children For Flu May Help Prevent Transmission, Protect Those Who Are Not Vaccinated Immunizing children and adolescents with inactivated influenza vaccine resulted in reduced rates of influenza in their community compared to a similar community in which children did not receive the vaccine, suggesting that vaccinating children may help prevent transmission of the virus and offer protection for unimmunized community residents, according to a study in the March 10 issue of JAMA... Dr. Alexander Varshavsky And Dr. Harmit Malik Awarded Vilcek Prizes In Biomedical Science The Vilcek Foundation is pleased to announce the granting of the 2010 Vilcek Prize for Biomedical Science to Dr. Alexander Varshavsky, the Howard & Gwen Laurie Smits Professor of Cell Biology at California Institute of Technology, for elucidating the process and biological significance of regulated protein degradation in living cells... Accelr8 Announces Acceptance Of Scientific Presentation, And Pilot Results With A New Rapid Test For A Major Emerging Resistance Threat Accelr8 Technology Corporation (NYSE Amex: AXK) announced that it has received acceptance to present results for a study on 2-hour, culture-free, quantitative pathogen identification. The study was co-authored with principal investigators at the Denver Health Medical Center and the Barnes-Jewish Hospital in St. Louis... What Is Rabies? What Causes Rabies? Rabies is a deadly virus. It is usually transmitted through saliva from the bite of an infected animal, into the bloodstream. The rabies virus is an infection of the central nervous system and causes inflammation of the brain. It is zoonotic, meaning it is transmitted by animals. If treated immediately after a bite, it is possible to prevent rabies... WHO Releases New Malaria Guidelines For Treatment And Procurement Of Medicines The World Health Organization (WHO) is releasing new guidelines for the treatment of malaria, and the first ever guidance on procuring safe and efficacious anti-malarial medicines. In recent years a new type of treatment called artemisinin-based combination therapy (ACTs) has transformed the treatment of malaria, but if not used properly the medicine could become ineffective... Federal Funds Support Health Depts., But Leadership Is Key - Study The surge of funds for bioterrorism preparedness over the past decade does not appear to be improving local public health resources in general, according to research from Purdue University... Chimerix Initiates Phase 2 Study Of CMX001 In Stem Cell Transplant Recipients Seropositive For Cytomegalovirus Chimerix, Inc., a biotechnology company developing orally-available antiviral therapeutics, announced the initiation of a multi-center Phase 2 clinical trial designed to evaluate CMX001 in stem cell transplant recipients who are seropositive for cytomegalovirus (CMV). CMX001 is a broad-spectrum antiviral agent with demonstrated activity against double-stranded DNA (dsDNA) viruses... Tetanus, Hepatitis Vaccination Campaign Launched In Chile Amid Fears Of Disease Outbreaks "Chile launched a hepatitis and tetanus vaccination campaign Friday and doctors warned of outbreaks of diarrhea and infection among thousands of people displaced by the earthquake and the tsunami that heavily damaged or destroyed 36 hospitals and made garbage dumps of coastal towns and cities," the Associated Press reports... Infectious Virus Hidden In Chromosomes During Latency Can Be Passed From Parents To Children Human herpesvirus 6 (HHV-6) infects nearly 100 percent of humans in early childhood, and the infection then lasts for the rest of a person's life... New Research Shows Immune Cells Use Bungee Of Death To Kill Dangerous Cells Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to research published in the Proceedings of the National Academy of Sciences. The study, by researchers from Imperial College London, shows that natural killer (NK) cells use this bungee to destroy cells that could otherwise escape them... Exploring Echinacea's Enigmatic Origins An Agricultural Research Service (ARS) scientist is helping to sort through the jumbled genetics of Echinacea, the coneflower known for its blossoms - and its potential for treating infections, inflammation, and other human ailments... Heat Therapy Shown Effective In Treating Cutaneous Leishmaniasis Among U.S. Soldiers In Iraq A single session of heat therapy using the Thermomed™ device appears to be as effective as a 10-day intravenous course of sodium stibogluconate (Pentostam) for the treatment of Leishmania major skin lesions, according to a new study by Naomi Aronson and her colleagues at the Uniformed Services University of the Health Sciences (USU) and Walter Reed Army Medical Center (WRAMC)... Dissolution Of The Meat Hygiene Service And Merger With The Food Standards Agency The Board of the Food Standards Agency (FSA) has decided to dissolve the executive agency status of the Meat Hygiene Service (MHS) and to bring its staff and functions into the FSA to form the core of a new FSA Operations Group... Xhale Innovations To Demonstrate The HyGreen Hand Hygiene System At The Fifth Decennial International Conference On Healthcare-Associated Infections Xhale Innovations (XI) announced today that it will showcase its hand hygiene system, HyGreen™, at the Fifth Decennial International Conference on Healthcare-Associated Infections to be held March 18 - 22, 2010. This real-time hand hygiene recording and reminding system is designed to assist healthcare facilities with their infection control programs. According to XI CTO, Dr... MicroPhage Seeks FDA Clearance To Market World's First Test Designed To Rapidly Identify Bacterial Infections And Antibiotic Susceptibility MicroPhage announced that it has submitted human data from a pivotal clinical study of its 'Microphage MRSA/MSSA Blood Culture Test' to support a U.S. Food and Drug Administration (FDA) 510(k) premarket notification process. The first of MicroPhage's instrument-free, rapid tests is based on the Company's patented Bacteriophage Amplification platform technology... Max Planck Scientists Develop A Fingerprint For Genes: New Strategy To Play Major Role In Research On Human Diseases Cells may not have a mouth, but they still need to ingest substances from the external environment. If this process - known as endocytosis - is affected, it can lead to infectious diseases or cardio-vascular diseases, cancer, Huntington's and diabetes... Vitamin D Crucial To Activating Immune Defenses Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defenses and that without sufficient intake of the vitamin, the killer cells of the immune system - T cells - will not be able to react to and fight off serious infections in the body... Consumer Advisory - Salmonella In Hydrolysed Vegetable Protein (HVP), Canada The Canadian Food Inspection Agency (CFIA), Health Canada and the Public Health Agency of Canada (PHAC) are closely following an investigation by U.S. authorities into possible Salmonella contamination of Hydrolysed Vegetable Protein (HVP) in the United States. HVP is used as a flavour enhancer in many commercially processed foods... Over-Utilization Of Intravenous Proton Pump Inhibitor In Non-Intensive Care Unit Patients Proton pump inhibitors (PPIs) are the most effective agents for treating acid related gastrointestinal (GI) disorders. The utilization of intravenous (IV) formulations of PPIs has dramatically increased in health care institutions for inappropriate indications, route of administration and length of treatment... Salmonella In HVP Additive Prompts Potentially Massive Processed Food Recall Thousands of types of processed foods containing hydrolyzed vegetable protein or HVP made by Basic Food Flavors Inc in Las Vegas, Nevada, may pose a health risk due to possible contamination with Salmonella Tennessee, said the US Food and Drug Administration last week... Successful Treatment Of Periodontal Disease Lowered Preterm Birth Incidences Previous studies have explored the effect of periodontal treatment, irrespective of efficacy of treatment, in reducing infant prematurity. In a study titled "Risk of Preterm Birth Is Reduced with Successful Periodontal Treatment," lead researcher M. Jeffcott, and colleagues S. Parry and M. Sammel (all from the University of Pennsylvania, Philadelphia) and G. Macones (Washington University, St... Polio Vaccination Campaign To Target 85M Children In 19 West, Central African Countries Global health organizations will launch a $30 million polio vaccination campaign on Saturday in West and Central Africa aimed at immunizing 85 million children under age 5, the Joint Global Polio Eradication Initiative and the International Federation of the Red Cross said on Thursday, Agence France-Presse reports (3/4)... Conference Calls For East African Countries To Prioritize Water, Sanitation Programs During a sanitation conference being held in Kampala, Uganda, this week, "experts have urged regional countries to prioritize programs aimed at increasing access to safe water and sanitation" to move them closer to reaching the Millennium Development Goals (MDGs) target in 2015, New Times/allAfrica.com reports... BioVex Initiates Phase 1 Clinical Trial With Its Genital Herpes Vaccine, ImmunoVEXHSV2 BioVex Inc, a private biotechnology company developing new generation biologics for the treatment of cancer and prevention of infectious disease, announced that the first subject had been dosed in the Phase 1 study of its live attenuated genital herpes vaccine, ImmunoVEXHSV2. The Phase 1 study is an open label ascending dose trial, assessing safety and immune response in healthy volunteers...
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